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Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics

Creator: Hariani, Gunjan D, Lam, Ernest J, Havener, Tammy, Kwok, Pui-Yan, McLeod, Howard L., Wagner, Michael J, Motsinger-Reif, Alison A

Abstract Background The goal of this study was to perform candidate gene association with cytotoxicity of chemotherapeutics in cell line models through resequencing and discovery of rare and low frequency variants along with common variations. Here, (more)

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13104_2013_article_2893.pdf

Collection: BioMed Central

Date Deposited: 2016-08-12

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Additional file 1: Supplementary tables and figures. Competing interests

Collection: BioMed Central

Date Deposited: 2016-08-12

Date Created: 2016-08-12

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Figure 1 Manhattan plot for association with oxaliplatin.

Collection: BioMed Central

Date Deposited: 2016-08-12

Date Created: 2016-08-12

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Figure 2 Linkage disequilibrium plot for MT1A.

Collection: BioMed Central

Date Deposited: 2016-08-12

Date Created: 2016-08-12

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