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Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor

Creator: Beltran, Adriana S, Rivenbark, Ashley G, Richardson, Bryan T, Yuan, Xinni, Quian, Haili, Hunt, John P, Zimmerman, Eric, Graves, Lee, Blancafort, Pilar

Abstract Introduction Tumor-initiating cells (TIC) are being extensively studied for their role in tumor etiology, maintenance and resistance to treatment. The isolation of TICs has been limited by the scarcity of this population in the tissue of (more)

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13058_2010_article_2751.pdf

Collection: BioMed Central

Date Deposited: 2017-01-20

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Additional file 10: Figure S4. NOS targets are over-represented across breast cancers.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 1: Table S1. Primer sequences

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 2: Supplementary methods.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 3: Table S2. Antibodies used in this study.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 6: Table S3. Summary of animal experiments.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 7: Table S4. Genes Up-regulated in OTBCs.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Additional file 8: Table S5. Genes Down-regulated in OTBCs.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Figure 10

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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Figure 2 OCT4-transduced breast cells (OTBCs) underwent an immortalization process.

Collection: BioMed Central

Date Deposited: 2017-01-20

Date Created: 2017-01-20

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