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Modeling human enteric dysbiosis and rotavirus immunity in gnotobiotic pigs

Creator: Twitchell, Erica L, Tin, Christine, Wen, Ke, Zhang, Husen, Becker-Dreps, Sylvia, Azcarate-Peril, Andrea, Vilchez, Samuel, Li, Guohua, Ramesh, Ashwin, Weiss, Mariah, Lei, Shaohua, Bui, Tammy, Yang, Xingdong, Schultz-Cherry, Stacey, Yuan, Lijuan

Abstract Background Rotavirus vaccines have poor efficacy in infants from low- and middle-income countries. Gut microbiota is thought to influence the immune response to oral vaccines. Thus, we developed a gnotobiotic (Gn) pig model of enteric (more)

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13099_2016_article_136.pdf

Collection: BioMed Central

Date Deposited: 2016-11-18

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Additional file 1: Table S1-S4

Collection: BioMed Central

Date Deposited: 2016-11-18

Date Created: 2016-11-18

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Additional file 2: Figure S1. Duodenum Histopathology

Collection: BioMed Central

Date Deposited: 2016-11-18

Date Created: 2016-11-18

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Additional file 3: Figure S2. Jejunum Histopathology

Collection: BioMed Central

Date Deposited: 2016-11-18

Date Created: 2016-11-18

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Additional file 4: Figure S3. Ileum Histopathology

Collection: BioMed Central

Date Deposited: 2016-11-18

Date Created: 2016-11-18

tiff  (14.6 MB)