The relationship between water intake and foetal growth and preterm delivery in a prospective cohort study

Public Deposited
Analytics

Downloadable Content

Download PDF
Request Version for Screen Reader
Creator
  • Wright, J Michael
    • Other Affiliation: National Center for Environmental Assessment, US Environmental Protection Agency, Cincinnati, Ohio, USA
  • Hoffman, Caroline S
    • Other Affiliation: Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
  • Savitz, David A
    • Other Affiliation: Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York, USA
Abstract
  • Background Interpretation of previous associations between water intake and adverse birth outcomes is challenging given that amount and type of water consumed can be non-specific markers of exposure or underlying behavioural characteristics. We examined the relationship between water intake measures and adverse birth outcomes in participants from three study sites in the United States. Methods Using a prospective cohort study, we examined daily intake of bottled, cold tap, total tap, and total water in relation to birth weight and risk of small-for-gestational-age (SGA) among term births and risk of preterm delivery. Results Based on water consumption data collected between 20-24 weeks of gestation, the adjusted mean birth weight was 27 (95% confidence interval [CI]: -34, 87), 39 (95% CI: -22, 99), and 50 (95% CI: -11, 110) grams higher for the upper three total water intake quartiles (> 51-78, > 78-114, and > 114 ounces/day) compared to the lowest quartile (≤ 51 ounces/day). Adjusted birth weight results were similar for bottled water, cold tap water, and total tap water intake. An exposure-response gradient was not detected for either preterm delivery or SGA with increasing total water intake and total tap water intake, but adjusted relative risks for all three upper quartiles were below 1.0 (range: 0.6-0.9) for SGA. Conclusion These data suggest that high water intake may be associated with higher mean birth weight following adjustment for confounding.
Date of publication
DOI
Identifier
Resource type
  • Article
Rights statement
  • In Copyright
Rights holder
  • J Michael Wright et al.; licensee BioMed Central Ltd.
License
Journal title
  • BMC Pregnancy and Childbirth
Journal volume
  • 10
Journal issue
  • 1
Page start
  • 48
Language
  • English
Is the article or chapter peer-reviewed?
  • Yes
ISSN
  • 1471-2393
Bibliographic citation
  • BMC Pregnancy and Childbirth. 2010 Aug 24;10(1):48
Publisher
  • BioMed Central Ltd
Access right
  • Open Access
Date uploaded
  • August 23, 2012

Relations

Parents:

This work has no parents.

Items

Thumbnail Title Date Uploaded Visibility Actions
file details 1471-2393-10-48.pdf 2019-05-06 Public Download
file details 1471-2393-10-48.xml 2019-05-06 Public Download