Removal of Ozone by the Extrathoracic and Intrathoracic Airways in Man
Public Deposited- Last Modified
- February 27, 2019
- Creator
-
Weaver, Richard A.
- Affiliation: Gillings School of Global Public Health, Department of Environmental Sciences and Engineering
- Abstract
- Extrathoracic and intrathoracic ozone removal were studied in eighteen healthy, nonsmoking volunteers using a controlled environmental chamber. Ozone-containing air was drawn through a polyethylene sampling tube placed through one nostril into the posterior pharynx, and analyzed with a rapidly responding ozone analyzer. Measurements were made using a randomized split-split plot design for each subject at ozone concentrations of 0.1 ppm, 0.2 ppm and 0.4 ppm, using three breathing modes (nasal, oronasal and mouth), and at two different breathing frequencies (12 and 24 BPM). For extrathoracic ozone removal, significant effects were demonstrated for mode of breathing and breathing frequency (both with p< 0.001), but not for ambient ozone concentration. For intrathoracic ozone removal, significant effects were demonstrated for ambient ozone concentration (p=0.032) and for breathing frequency (p<0.001), but not for mode of breathing. Mechanisms are postulated to explain the results obtained.
- Date of publication
- August 1986
- DOI
- Resource type
- Rights statement
- In Copyright
- Advisor
- Gerrity, Timothy R.
- Fraser, David A.
- Reist, Parker C.
- Degree
- Master of Public Health
- Academic concentration
- Industrial Hygiene
- Degree granting institution
- University of North Carolina at Chapel Hill
- Graduation year
- 1986
- Language
- Deposit record
- 4229e0fb-b010-4ede-aa50-9d4a2f0726fb
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