The cancer genome atlas pan-cancer analysis project

The Cancer Genome Atlas Research Network; Weinstein, John N.; Collisson, Eric A.; Mills, Gordon B.; Mills Shaw, Kenna R.; Ozenberger, Brad A.; Ellrott, Kyle; Shmulevich, Ilya; Sander, Chris; Stuart, Joshua M.

Creator

The Cancer Genome Atlas Research Network
Weinstein, John N.
- Other Affiliation: Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Collisson, Eric A.
- Other Affiliation: Department of Medicine, University of California, San Francisco, San Francisco, California, USA
Mills, Gordon B.
- Other Affiliation: Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Mills Shaw, Kenna R.
- Other Affiliation: The Cancer Genome Atlas Program Office, Center for Cancer Genomics, National Cancer Institute, Bethesda, Maryland, USA. University of Texas MD Anderson Cancer Center, Institute for Personalized Cancer Therapy, Houston, Texas, USA
Ozenberger, Brad A.
- Other Affiliation: National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA
Ellrott, Kyle
- Other Affiliation: Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, California, USA. Center for Biomolecular Science and Engineering, University of California, Santa Cruz, Santa Cruz, California, USA
Shmulevich, Ilya
- Other Affiliation: Institute for Systems Biology, Seattle, Washington, USA
Sander, Chris
- Other Affiliation: Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, USA
Stuart, Joshua M.
- Other Affiliation: Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, California, USA. Center for Biomolecular Science and Engineering, University of California, Santa Cruz, Santa Cruz, California, USA

Abstract

The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.

Date of publication

2013

DOI

https://doi.org/10.17615/670y-yr53

Identifier

2-s2.0-84884994218
https://doi.org/10.1038/ng.2764

Related resource URL

https://www.nature.com/articles/ng.2764

Resource type

Journal Item

Rights statement

In Copyright

Journal title

Nature Genetics

Journal volume

Journal issue

Page start

1113

Page end

1120

Language

English

Version

Postprint

Note

The Cancer Genome Atlas Research Network full lists of members and affiliations: Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Rehan Akbani, Keith A Baggerly, Bradley Broom, Tod D Casasent, James Cleland, Deepti Dodda, Leng Han, Shelley M Herbrich, Zhenlin Ju, Hoon Kim, Jun Li, Han Liang, Wenbin Liu, Philip L Lorenzi, James Melott, Lam Nguyen, Xiaoping Su, Roeland Verhaak, Wenyi Wang, John N Weinstein, Andrew Wong, Yang Yang, Rong Yao, Kosuke Yoshihara, Yuan Yuan, Nianxiang Zhang, Siyuan Zheng & David W Kane; Department of Systems Biology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Yiling Lu, Gordon B Mills, John N Weinstein & Michael Ryan; Department of Medicine, University of California, San Francisco, San Francisco, California, USA: Barry S Taylor & Eric A Collisson; The Cancer Genome Atlas Program Office, Center for Cancer Genomics, National Cancer Institute, Bethesda, Maryland, USA: Kenna R Mills Shaw; University of Texas MD Anderson Cancer Center, Institute for Personalized Cancer Therapy, Houston, Texas, USA: Kenna R Mills Shaw; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA: Brad A Ozenberger & Heidi Sofia; Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, California, USA: Daniel Carlin, Melisssa Cline, Brian Craft, Kyle Ellrott, Mary Goldman, David Haussler, Singer Ma, Sam Ng, Evan Paull, Amie Radenbaugh, Sofie Salama, Artem Sokolov, Joshua M Stuart, Teresa Swatloski, Vladislav Uzunangelov, Peter Waltman & Jing Zhu; Center for Biomolecular Science and Engineering, University of California, Santa Cruz, Santa Cruz, California, USA: Daniel Carlin, Melisssa Cline, Brian Craft, Kyle Ellrott, Mary Goldman, David Haussler, Singer Ma, Sam Ng, Evan Paull, Amie Radenbaugh, Sofie Salama, Artem Sokolov, Joshua M Stuart, Teresa Swatloski, Vladislav Uzunangelov, Peter Waltman & Jing Zhu; Institute for Systems Biology, Seattle, Washington, USA: Brady Bernard, Ryan Bressler, Andrea Eakin, Lisa Iype, Theo Knijnenburg, Roger Kramer, Richard Kreisberg, Kalle Leinonen, Jake Lin, Michael Miller, Sheila M Reynolds, Hector Rovira, Ilya Shmulevich & Vesteinn Thorsson; Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, USA: B Arman Aksoy, Giovanni Ciriello, Gideon Dresdner, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Andre Kahles, William Lee, Kjong-Van Lehmann, Martin L Miller, Ricardo Ramirez, Gunnar Rätsch, Boris Reva, Chris Sander, Nikolaus Schultz, Yasin Senbabaoglu, Rileen Sinha, S Onur Sumer, Yichao Sun & Nils Weinhold; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA: Kyle Chang, Chad J Creighton, Caleb Davis, Lawrence Donehower, Jennifer Drummond, David Wheeler, Min Wang, Huyen Dinh, Harsha Vardhan Doddapaneni, Richard Gibbs, Preethi Gunaratne, Yi Han, Divya Kalra, Christie Kovar, Lora Lewis, Margaret Morgan, Donna Morton, Donna Muzny, Jeffrey Reid & Liu Xi; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada: Adrian Ally, Miruna Balasundaram, Inanc Birol, Yaron S N Butterfield, Andy Chu, Eric Chuah, Hye-Jung E Chun, Noreen Dhalla, Ranabir Guin, Martin Hirst, Carrie Hirst, Robert A Holt, Steven J M Jones, Darlene Lee, Haiyan I Li, Marco A Marra, Michael Mayo, Richard A Moore, Andrew J Mungall, A Gordon Robertson, Jacqueline E Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen & Richard J Varhol; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada: Inanc Birol; School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada: Inanc Birol; The Eli and Edythe L. Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA: Rameen Beroukhim, Ami S Bhatt, Angela N Brooks, Andrew D Cherniack, Samuel S Freeman, Stacey B Gabriel, Elena Helman, Joonil Jung, Matthew Meyerson, Akinyemi I Ojesina, Chandra Sekhar Pedamallu, Gordon Saksena, Steven E Schumacher, Barbara Tabak, Travis Zack, Eric S Lander, Scott L Carter, Kristian Cibulskis, Lynda Chin, Gad Getz, Carrie Sougnez, Juok Cho, Daniel DiCara, Scott Frazer, Nils Gehlenborg, David I Heiman, Jaegil Kim, Michael S Lawrence, Pei Lin, Yingchun Liu, Michael S Noble, Petar Stojanov, Doug Voet, Hailei Zhang, Lihua Zou & Chip Stewart; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA: Ami S Bhatt, Matthew Meyerson, Akinyemi I Ojesina, Chandra Sekhar Pedamallu & Petar Stojanov; Dana-Farber Cancer Institute, Boston, Massachusetts, USA: Angela N Brooks; Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts, USA: Elena Helman; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA: Steven E Schumacher & Barbara Tabak; Biophysics Program, Harvard University, Boston, Massachusetts, USA: Travis Zack; Institute for Applied Cancer Science, Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Christopher A Bristow, Harshad S Mahadeshwar, Alexei Protopopov, Sahil Seth, Xingzhi Song, Jiabin Tang, Dong Zeng, Lynda Chin, Jianhua Zhang, Chang-Jiun Wu & Chia-Chin Wu; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA: Angela Hadjipanayis, Angeliki Pantazi, Michael Parfenov, Xiaojia Ren, Netty Santoso & Jonathan Seidman; The Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA: Psalm Haseley, Semin Lee, Eunjung Lee, Lovelace J Luquette, Peter J Park, Ruibin Xi, Andrew W Xu, Lixing Yang & Nils Gehlenborg; Harvard Medical School–Partners HealthCare Center for Genetics and Genomics, Boston, Massachusetts, USA: Raju Kucherlapati; Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA: Peter J Park; Informatics Program, Children's Hospital, Boston, Massachusetts, USA: Peter J Park; School of Mathematical Sciences, Peking University, Beijing, China: Ruibin Xi; Center for Statistical Science, Peking University, Beijing, China: Ruibin Xi; Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: J Todd Auman; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Saianand Balu, Cheng Fan, Katherine A Hoadley, Shaowu Meng, Joel S Parker, Charles M Perou, Yan Shi, Grace O Silva, Scot Waring, Junyuan Wu, Wei Zhao, Tom Bodenheimer, D Neil Hayes, Alan P Hoyle, Stuart R Jeffreys, Lisle E Mose, Janae V Simons & Mathew G Soloway; Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Elizabeth Buda, Corbin D Jones & Scot Waring; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Corbin D Jones; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Piotr A Mieczkowski, Joel S Parker, Charles M Perou, Grace O Silva, Donghui Tan, Umadevi Veluvolu, Matthew D Wilkerson & Wei Zhao; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Charles M Perou; Research Computing Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: Jeffrey Roach; Department of Internal Medicine, Division of Medical Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA: D Neil Hayes; Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA: Stephen B Baylin & James G Herman; USC Epigenome Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA: Benjamin P Berman, Moiz S Bootwalla, Toshinori Hinoue, Peter W Laird, Suhn K Rhie, Hui Shen, Timothy Triche & Daniel J Weisenberger; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA: Ludmila Danilova; Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA: Gad Getz; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA: Gad Getz; Department of Biology and Biochemistry, University of Houston, Houston, Texas, USA: Preethi Gunaratne; University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Da Yang, Wei Zhang & Stanley R Hamilton; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Samirkumar Amin; In Silico Solutions, Fairfax, Virginia, USA: Kenneth Aldape, James Cleland, Lam Nguyen, Andrew Wong & Michael Ryan; Baylor College of Medicine, Houston, Texas, USA: Chad Creighton; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Yuexin Liu & Mary Edgerton; Department of Urology, Baylor College of Medicine, Houston, Texas, USA: Seth Lerner; Division of Biostatistics, University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas, USA: Yang Yang; Neuro-Oncology Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USA: Jun Yao & Alfred K Yung; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, USA: Yuan Yuan; SRA International, Inc., Fairfax, Virginia, USA: David W Kane, Mark A Jensen, Ari Kahn, Todd Pihl, David Pot & Yunhu Wan; Department of Pathology and Human Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA: Marc Ladanyi;Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA: Marc Ladanyi; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA: Ronglai Shen & Barry S Taylor; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA: Barry S Taylor; Molecular & Medical Genetics, Oregon Health & Science University, Portland, Oregon, USA: Suzanne Fei & Paul Spellman; Buck Institute for Research on Aging, Novato, California, USA: Christopher Benz & Christina Yau; Howard Hughes Medical Institute, University of California, Santa Cruz, Santa Cruz, California, USA: David Haussler & Sofie Salama; The Genome Institute, Washington University, St. Louis, Missouri, USA: Scott Abbott, Rachel Abbott, Nathan D Dees, Kim Delehaunty, Li Ding, David J Dooling, Jim M Eldred, Catrina C Fronick, Robert Fulton, Lucinda L Fulton, Joelle Kalicki-Veizer, Krishna-Latha Kanchi, Cyriac Kandoth, Daniel C Koboldt, David E Larson, Timothy J Ley, Ling Lin, Charles Lu, Vincent J Magrini, Elaine R Mardis, Michael D McLellan, Joshua F McMichael, Christopher A Miller, Michelle O'Laughlin, Craig Pohl, Heather Schmidt, Scott M Smith, Jason Walker, John W Wallis, Michael C Wendl, Richard K Wilson, Todd Wylie & Qunyuan Zhang; Department of Medicine, Washington University, St. Louis, Missouri, USA: Li Ding; Siteman Cancer Center, Washington University, St. Louis, Missouri, USA: Li Ding, Elaine R Mardis & Richard K Wilson; Division of Oncology, Washington University, St. Louis, Missouri, USA: Timothy J Ley; Department of Genetics, Washington University, St. Louis, Missouri, USA: Elaine R Mardis, Michael C Wendl, Richard K Wilson & Qunyuan Zhang; Department of Mathematics, Washington University, St. Louis, Missouri, USA: Michael C Wendl; SAIC-Frederick, Inc., Frederick, Maryland, USA: Robert Burton; Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA: Douglas A Levine; The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA: Aaron D Black, Jay Bowen, Jessica Frick, Julie M Gastier-Foster, Hollie A Harper, Carmen Helsel, Kristen M Leraas, Tara M Lichtenberg, Cynthia McAllister, Nilsa C Ramirez, Samantha Sharpe, Lisa Wise & Erik Zmuda; The Ohio State University, Columbus, Ohio, USA: Julie M Gastier-Foster & Nilsa C Ramirez; National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA: Stephen J Chanock, Tanja Davidsen, John A Demchok, Ina Felau, Margi Sheth, Louis Staudt, Roy Tarnuzzer, Zhining Wang, Liming Yang & Jiashan Zhang; Scimentis, Statham, Georgia, USA: Greg Eley; Sage Bionetworks, Seattle, Washington, USA: Larsson Omberg & Adam Margolin Department of Computer Science, Brown University, Providence, Rhode Island, USA: Benjamin J Raphael, Fabio Vandin, Hsin-Ta Wu & Mark D M Leiserson; Five3 Genomics, LLC, Santa Cruz, California, USA: Stephen C Benz & Charles J Vaske; Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil: Houtan Noushmehr Center for Integrative Systems Biology (CISBi), NAP/USP, São Paulo, Brazil: Houtan Noushmehr; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA: Denise Wolf & Laura Van't Veer; Department of Electrical Engineering, Columbia University, New York, New York, USA: Dimitris Anastassiou & Tai-Hsien Ou Yang; Research Unit on Biomedical Informatics, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain: Nuria Lopez-Bigas, Abel Gonzalez-Perez & David Tamborero; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain: Nuria Lopez-Bigas; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA: Zheng Xia & Wei Li; National Center for Biotechnology Information, National Library of Medicine, US National Institutes of Health, Bethesda, Maryland, USA: Dong-Yeon Cho & Teresa Przytycka; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA: Mark Hamilton & Sean McGuire; Institution for Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden: Sven Nelander, Patrik Johansson & Teresia Kling; Science for Life Laboratory, Uppsala University, Uppsala, Sweden: Sven Nelander, Patrik Johansson & Teresia Kling; Mathematical Sciences, University of Gothenburg/Chalmers, Gothenburg, Sweden: Rebecka Jörnsten & Jose Sanchez; Consortia The Cancer Genome Atlas Research Network Genome Characterization Center: Kyle Chang, Chad J Creighton, Caleb Davis, Lawrence Donehower, Jennifer Drummond, David Wheeler, Adrian Ally, Miruna Balasundaram, Inanc Birol, Yaron S N Butterfield, Andy Chu, Eric Chuah, Hye-Jung E Chun, Noreen Dhalla, Ranabir Guin, Martin Hirst, Carrie Hirst, Robert A Holt, Steven J M Jones, Darlene Lee, Haiyan I Li, Marco A Marra, Michael Mayo, Richard A Moore, Andrew J Mungall, A Gordon Robertson, Jacqueline E Schein, Payal Sipahimalani, Angela Tam, Nina Thiessen, Richard J Varhol, Rameen Beroukhim, Ami S Bhatt, Angela N Brooks, Andrew D Cherniack, Samuel S Freeman, Stacey B Gabriel, Elena Helman, Joonil Jung, Matthew Meyerson, Akinyemi I Ojesina, Chandra Sekhar Pedamallu, Gordon Saksena, Steven E Schumacher, Barbara Tabak, Travis Zack, Eric S Lander, Christopher A Bristow, Angela Hadjipanayis, Psalm Haseley, Raju Kucherlapati, Semin Lee, Eunjung Lee, Lovelace J Luquette, Harshad S Mahadeshwar, Angeliki Pantazi, Michael Parfenov, Peter J Park, Alexei Protopopov, Xiaojia Ren, Netty Santoso, Jonathan Seidman, Sahil Seth, Xingzhi Song, Jiabin Tang, Ruibin Xi, Andrew W Xu, Lixing Yang, Dong Zeng, J Todd Auman, Saianand Balu, Elizabeth Buda, Cheng Fan, Katherine A Hoadley, Corbin D Jones, Shaowu Meng, Piotr A Mieczkowski, Joel S Parker, Charles M Perou, Jeffrey Roach, Yan Shi, Grace O Silva, Donghui Tan, Umadevi Veluvolu, Scot Waring, Matthew D Wilkerson, Junyuan Wu, Wei Zhao, Tom Bodenheimer, D Neil Hayes, Alan P Hoyle, Stuart R Jeffreys, Lisle E Mose, Janae V Simons, Mathew G Soloway, Stephen B Baylin, Benjamin P Berman, Moiz S Bootwalla, Ludmila Danilova, James G Herman, Toshinori Hinoue, Peter W Laird, Suhn K Rhie, Hui Shen, Timothy Triche, Daniel J Weisenberger, Scott L Carter, Kristian Cibulskis, Lynda Chin, Jianhua Zhang, Gad Getz, Carrie Sougnez & Min Wang; Genome Data Analysis Center: Gordon Saksena, Scott L Carter, Kristian Cibulskis, Lynda Chin, Jianhua Zhang, Gad Getz, Huyen Dinh, Harsha Vardhan Doddapaneni, Richard Gibbs, Preethi Gunaratne, Yi Han, Divya Kalra, Christie Kovar, Lora Lewis, Margaret Morgan, Donna Morton, Donna Muzny, Jeffrey Reid, Liu Xi, Juok Cho, Daniel DiCara, Scott Frazer, Nils Gehlenborg, David I Heiman, Jaegil Kim, Michael S Lawrence, Pei Lin, Yingchun Liu, Michael S Noble, Petar Stojanov, Doug Voet, Hailei Zhang, Lihua Zou, Chip Stewart, Brady Bernard, Ryan Bressler, Andrea Eakin, Lisa Iype, Theo Knijnenburg, Roger Kramer, Richard Kreisberg, Kalle Leinonen, Jake Lin, Yuexin Liu, Michael Miller, Sheila M Reynolds, Hector Rovira, Ilya Shmulevich, Vesteinn Thorsson, Da Yang, Wei Zhang, Samirkumar Amin, Chang-Jiun Wu, Chia-Chin Wu, Rehan Akbani, Kenneth Aldape, Keith A Baggerly, Bradley Broom, Tod D Casasent, James Cleland, Chad Creighton, Deepti Dodda, Mary Edgerton, Leng Han, Shelley M Herbrich, Zhenlin Ju, Hoon Kim, Seth Lerner, Jun Li, Han Liang, Wenbin Liu, Philip L Lorenzi, Yiling Lu, James Melott, Gordon B Mills, Lam Nguyen, Xiaoping Su, Roeland Verhaak, Wenyi Wang, John N Weinstein, Andrew Wong, Yang Yang, Jun Yao, Rong Yao, Kosuke Yoshihara, Yuan Yuan, Alfred K Yung, Nianxiang Zhang, Siyuan Zheng, Michael Ryan, David W Kane, B Arman Aksoy, Giovanni Ciriello, Gideon Dresdner, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Andre Kahles, Marc Ladanyi, William Lee, Kjong-Van Lehmann, Martin L Miller, Ricardo Ramirez, Gunnar Rätsch, Boris Reva, Chris Sander, Nikolaus Schultz, Yasin Senbabaoglu, Ronglai Shen, Rileen Sinha, S Onur Sumer, Yichao Sun, Barry S Taylor, Nils Weinhold, Suzanne Fei, Paul Spellman, Christopher Benz, Daniel Carlin, Melisssa Cline, Brian Craft, Kyle Ellrott, Mary Goldman, David Haussler, Singer Ma, Sam Ng, Evan Paull, Amie Radenbaugh, Sofie Salama, Artem Sokolov, Joshua M Stuart, Teresa Swatloski, Vladislav Uzunangelov, Peter Waltman, Christina Yau, Jing Zhu & Stanley R Hamilton; Sequencing Center: Gad Getz, Carrie Sougnez, Scott Abbott, Rachel Abbott, Nathan D Dees, Kim Delehaunty, Li Ding, David J Dooling, Jim M Eldred, Catrina C Fronick, Robert Fulton, Lucinda L Fulton, Joelle Kalicki-Veizer, Krishna-Latha Kanchi, Cyriac Kandoth, Daniel C Koboldt, David E Larson, Timothy J Ley, Ling Lin, Charles Lu, Vincent J Magrini, Elaine R Mardis, Michael D McLellan, Joshua F McMichael, Christopher A Miller, Michelle O'Laughlin, Craig Pohl, Heather Schmidt, Scott M Smith, Jason Walker, John W Wallis, Michael C Wendl, Richard K Wilson, Todd Wylie & Qunyuan Zhang; Data Coordinating Center: Robert Burton, Mark A Jensen, Ari Kahn, Todd Pihl, David Pot & Yunhu Wan; Tissue Source Site: Douglas A Levine; Biospecimen Core Resource Center: Aaron D Black, Jay Bowen, Jessica Frick, Julie M Gastier-Foster, Hollie A Harper, Carmen Helsel, Kristen M Leraas, Tara M Lichtenberg, Cynthia McAllister, Nilsa C Ramirez, Samantha Sharpe, Lisa Wise & Erik Zmuda; National Cancer Institute/National Human Genome Research Institute Project Team: Stephen J Chanock, Tanja Davidsen, John A Demchok, Greg Eley, Ina Felau, Brad A Ozenberger, Margi Sheth, Heidi Sofia, Louis Staudt, Roy Tarnuzzer, Zhining Wang, Liming Yang & Jiashan Zhang; Collaborators: Larsson Omberg, Adam Margolin, Benjamin J Raphael, Fabio Vandin, Hsin-Ta Wu, Mark D M Leiserson, Stephen C Benz, Charles J Vaske, Houtan Noushmehr, Theo Knijnenburg, Denise Wolf, Laura Van't Veer, Eric A Collisson, Dimitris Anastassiou, Tai-Hsien Ou Yang, Nuria Lopez-Bigas, Abel Gonzalez-Perez, David Tamborero, Zheng Xia, Wei Li, Dong-Yeon Cho, Teresa Przytycka, Mark Hamilton, Sean McGuire, Sven Nelander, Patrik Johansson, Rebecka Jörnsten, Teresia Kling & Jose Sanchez

ISSN

1061-4036

The cancer genome atlas pan-cancer analysis project

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The cancer genome atlas pan-cancer analysis project

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