Background: Endometriosis affects 2.5-3.3% of reproductive age women and is a common diagnosis among women with chronic pelvic pain. Treatment for endometriosis ranges from conservative medical therapies to radical surgery. Endometriosis is an indication for 25-35% of laparoscopies and 10-15% of hysterectomies each year. Although the majority of women with endometriosis respond to conservative medical therapy, those with persistent pain often undergo hysterectomy. However, there exists limited data on the contribution of disease specific (e.g. stage of endometriosis) versus non-specific (e.g. biopsychosocial) factors on treatment outcomes (e.g. clinical pain report). We sought to investigate these factors at baseline as well as short and long term follow-up intervals for surgical endometriosis patients. Objective: To evaluate the contribution of disease specific versus biopsychosocial factors on surgical treatment outcomes at 1-year and 3-6 years post-surgery for endometriosis.