Prepregnancy BMI and Preeclampsia: Review of the Literature and Public Health Implications
Public Deposited- Last Modified
- November 21, 2019
- Creator
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Zabih, Weeda
- Affiliation: Gillings School of Global Public Health, Department of Maternal and Child Health
- Abstract
- Objective: With increasing prevalence of obesity, there is increased attention on prepregnancy BMI and its relation to pregnancy outcomes. Quantifying the relationship between Body Mass Index (BMI) and preeclampsia may provide rationale for a preconception target for intervention that may affect the incidence of preeclampsia. A review of the literature was performed to explore the relationship between prepregnancy BMI and the risk of preeclampsia. Methods: PubMed, Embase and Google Scholar were searched for epidemiologic studies (with BMI as a main exposure and preeclampsia as one of the main outcomes) in English published between 2000 and 2013. For each study a summary of study characteristics, main findings and methodology were reviewed and summarized. Results: BMI is consistently shown to be significantly associated with increased risk for preeclampsia, with ORs ranging from 1.7 to 7. This association appears independent of race/ethnicity, and the association is stronger as the BMI class increases from overweight to superobese. Conclusions: Prepregnancy BMI is associated with increased odds of preeclampsia. Public health interventions that focus on preconception normalization of BMI in women of reproductive age may impact the incidence of preeclampsia and its associated morbidity.
- Date of publication
- May 2013
- DOI
- Resource type
- Rights statement
- In Copyright
- Note
- Paper type: Review
- Advisor
- Margolis, Lewis
- Degree
- Master of Public Health
- Degree granting institution
- University of North Carolina at Chapel Hill
- Graduation year
- 2013
- Language
- Deposit record
- 564d1737-ca9b-4211-9c3e-c1926665c3df
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