International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)

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  • Wilson, Jacob M
    • Other Affiliation: Department of Health Sciences and Human Performance, University of Tampa, Tampa, FL, USA
  • Fitschen, Peter J
    • Other Affiliation: Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA
  • Campbell, Bill
    • Other Affiliation: Exercise and Performance Nutrition Laboratory, Dept. of Physical Education and Exercise Science, University of South Florida, 4202 E. Fowler Avenue, PED 214, Tampa, FL, 33620, USA
  • Wilson, Gabriel J
    • Other Affiliation: Department of Nutritional Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA
  • Zanchi, Nelo
    • Other Affiliation: Laboratory of Applied Nutrition and Metabolism, Physical Education and School of Sports, University of São Paulo, São Paulo, Brazil
  • Taylor, Lem
    • Other Affiliation: Human Performance Laboratory, Exercise & Sport Science Department, University of Mary Hardin-Baylor, Belton, TX, 76513, USA
  • Wilborn, Colin
    • Other Affiliation: Human Performance Laboratory, Exercise & Sport Science Department, University of Mary Hardin-Baylor, Belton, TX, 76513, USA
  • Kalman, Douglas S
    • Other Affiliation: Miami Research Associates, Endocrinology & Nutrition Department, 6141 Sunset Drive - Suite 301, Miami, FL, 33143, USA
  • Stout, Jeffrey R
    • Other Affiliation: Institute of Exercise Physiology and Wellness, University of Central Florida, Orlando, FL, 32816, USA
  • Hoffman, Jay R
    • Other Affiliation: Institute of Exercise Physiology and Wellness, University of Central Florida, Orlando, FL, 32816, USA
  • Ziegenfuss, Tim N
    • Other Affiliation: The Center for Applied Health Sciences, Stow, OH, 44224, USA
  • Lopez, Hector L
    • Other Affiliation: The Center for Applied Health Sciences, Stow, OH, 44224, USA; Supplement Safety Solutions, Bedford, MA, USA
  • Kreider, Richard B
    • Other Affiliation: Exercise & Sport Nutrition Lab, Department of Health & Kinesiology, Texas A&M University, College Station, TX, USA
  • Smith-Ryan, Abbie
    • Affiliation: College of Arts and Sciences, Department of Exercise and Sport Science
    • Other Affiliation: Applied Physiology Laboratory
  • Antonio, Jose
    • Other Affiliation: Exercise and Sports Science, Nova Southeastern University, Davie, FL, 33314, USA
Abstract
  • Abstract Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature on the use of beta-hydroxy-beta-methylbutyrate (HMB) as a nutritional supplement. The ISSN has concluded the following. 1. HMB can be used to enhance recovery by attenuating exercise induced skeletal muscle damage in trained and untrained populations. 2. If consuming HMB, an athlete will benefit from consuming the supplement in close proximity to their workout. 3. HMB appears to be most effective when consumed for 2 weeks prior to an exercise bout. 4. Thirty-eight mg·kg·BM-1 daily of HMB has been demonstrated to enhance skeletal muscle hypertrophy, strength, and power in untrained and trained populations when the appropriate exercise prescription is utilized. 5. Currently, two forms of HMB have been used: Calcium HMB (HMB-Ca) and a free acid form of HMB (HMB-FA). HMB-FA may increase plasma absorption and retention of HMB to a greater extent than HMB-CA. However, research with HMB-FA is in its infancy, and there is not enough research to support whether one form is superior. 6. HMB has been demonstrated to increase LBM and functionality in elderly, sedentary populations. 7. HMB ingestion in conjunction with a structured exercise program may result in greater declines in fat mass (FM). 8. HMB’s mechanisms of action include an inhibition and increase of proteolysis and protein synthesis, respectively. 9. Chronic consumption of HMB is safe in both young and old populations.
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  • Article
Rights statement
  • In Copyright
Rights holder
  • Jacob M Wilson et al.; licensee BioMed Central Ltd.
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Journal title
  • Journal of the International Society of Sports Nutrition
Journal volume
  • 10
Journal issue
  • 1
Page start
  • 6
Language
  • English
Is the article or chapter peer-reviewed?
  • Yes
ISSN
  • 1550-2783
Bibliographic citation
  • Journal of the International Society of Sports Nutrition. 2013 Feb 02;10(1):6
Publisher
  • BioMed Central Ltd
Access right
  • Open Access
Date uploaded
  • February 9, 2013

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