Binge Alcohol Consumption Does Not Induce IL-10 Immune Response in the Ventral Tegmental Area of the Mouse Brain
Public Deposited- Last Modified
- February 26, 2019
- Creator
-
Daji, Akshay
- Affiliation: College of Arts and Sciences, Department of Biology
- Abstract
- The goal of this study was to determine the effects of binge ethanol consumption on the levels of expression of IL-10 in the VTA of the mesolimbic pathway utilizing the DID protocol. In this study an immunohistochemical assessment is used to measure IL-10 expression in the VTA. A lack of an IL-10 anti-inflammatory immune response or a decrease in basal IL-10 levels in the VTA could be a possible factor intensifying the inflammation of the mesolimbic reward pathway that underlies the behavioral maladaptations that lead to alcoholism.
- Date of publication
- spring 2017
- Keyword
- DOI
- Resource type
- Rights statement
- In Copyright
- Note
- Funding: None
- Advisor
- Thiele, Todd
- Degree
- Bachelor of Science
- Academic concentration
- Biology
- Honors level
- Honors
- Degree granting institution
- University of North Carolina at Chapel Hill
- Graduation year
- 2017
- Language
- English
Relations
- Parents:
This work has no parents.
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IL-10 Paper APPROVED DRAFT.pdf | 2019-05-18 | Public | Download |