Distinguishing Features of Autism in Boys with Fragile X Syndrome

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  • March 20, 2019
Creator
  • Brock, Matt
    • Affiliation: School of Education
Abstract
  • Children with fragile X syndrome (FXS) have a much higher prevalence of autism than typical children in the general population. Children with comorbid FXS and autism represent a distinct subgroup of children with FXS that is at risk for markedly poorer outcomes. Evidence shows that early identification and intervention can improve outcomes. To further efforts to create a specialized autism screener for young males with FXS that could assist in early identification, this study explores the association of selected parent-report questionnaire items with autism symptoms in a sample of 60 boys with FXS, ages 4-18 years old. Findings demonstrate that both social and repetitive behaviors distinguish children with comorbid FXS and autism from children with only FXS, with repetitive behaviors playing a much more prominent role than previously documented in the literature. The results of this study provide evidence that a well designed parent-report questionnaire that focuses on specific distinguishing behaviors might serve as an effective tool for early identification of autism in the FXS population.
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  • In Copyright
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  • Boone, Harriet
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  • Open access
Date uploaded
  • October 11, 2010

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