An Evaluation of the Effectiveness of the HPV Vaccine in Preventing Cervical Disease Among Young Women at Duke

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  • January 13, 2020
Creator
  • Smelick, Gillian
    • Affiliation: Gillings School of Global Public Health, Public Health Leadership Program
Abstract
  • The objective of this study was to evaluate the effectiveness of the Human Papilloma Virus (HPV) vaccine in preventing HPV-related cervical disease and genital warts among young women receiving health care services from Duke Health. A retrospective review of filtered electronic medical record (EMR) data was performed to identify women ages 18-34 years old with HPV-related diagnoses of interest from 2000-2015. The annual overall, age-specific and race-specific incidences of each considered diagnosis were then calculated for the State of North Carolina using the EMR data and publicly available census data. Overall NC county-level incidences were also calculated. The calculated incidences were generally downward trending over the study period across all HPV-related diagnoses for the younger evaluated age groups (18-19 years old and 20-24 years old) while results were less consistent for women ages 25-34 years old. A 2015 increase in the overall incidence of all considered diagnoses except high risk HPV infection was observed and appears to have been driven largely by women 25-34 years old. The annual incidence of all considered diagnoses were consistently higher among African American women than Caucasian women, suggesting the need for further research to evaluate potential causes of these disparate racial outcomes and potential strategies to address them.
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  • In Copyright
Note
  • Track: HC&P
  • Paper type: Research or research design
Advisor
  • Viera, Anthony
Reviewer
  • Muasher, Lisa
Degree
  • Master of Public Health
Academic concentration
  • Public Health
Degree granting institution
  • University of North Carolina at Chapel Hill
Graduation year
  • 2017
Language
Deposit record
  • a99ece62-5527-423d-93e6-9da12560b9fb

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