Biliary Atresia: A Case Report

Public Deposited
Analytics

Downloadable Content

Download PDF
Request Version for Screen Reader
Last Modified
  • February 28, 2019
Creator
  • Levey, Leah
    • Affiliation: Gillings School of Global Public Health, Department of Nutrition
Abstract
  • Biliary Atresia (BA) is characterized by a progressive obliteration of all, or part of, the extrahepatic biliary tree. It is the primary indication for pediatric liver transplantation, responsible for approximately 50% of all pediatric liver transplants. The resting energy expenditure of children living with BA is 30-50% higher than that of healthy children of the same age because children with BA must consume additional calories to promote liver regeneration. BA prevents bile from traveling from the liver into the intestine, where it is crucial for fat absorption. Bile insufficiency in the intestine results in malnutrition, malabsorption, and fat-soluble vitamin (ADEK) deficiencies. Sixty to 80% of children with end-stage liver disease exhibit moderate to severe malnutrition before liver transplantation. By examining a child living with BA hospitalized at UNC-Hospitals, I explored the medical nutrition therapy for patients with BA before liver transplantation. According to the most recent research, the best nutritional treatment for BA patients before liver transplantation includes cycled EN nocturnal feeding with daily oral feeds using formula with a high MCT:LCT ratio. To prevent deficiencies, it is strongly recommended that BA patients be provided with 130-150% of the caloric DRI for age, 2.5-3 g/kg/d of protein, and ADEK supplements.
Date of publication
Keyword
DOI
Resource type
Rights statement
  • In Copyright
Advisor
  • Coleman, Rosalind
Degree
  • Master of Public Health
Academic concentration
  • Clinical Nutrition
Degree granting institution
  • University of North Carolina at Chapel Hill
Graduation year
  • 2016
Language
Deposit record
  • 749147b1-ae14-4226-b127-7b4634a03c23

Relations

Parents:

This work has no parents.

Items

Thumbnail Title Date Uploaded Visibility Actions
file details Final Draft.pdf 2019-04-26 Public Download