The associations of parity and maternal age with small-for-gestational-age, preterm, and neonatal and infant mortality: a meta-analysis
Public DepositedAdd to collection
You do not have access to any existing collections. You may create a new collection.
Downloadable Content
Download PDFCitation
MLA
Kozuki, Naoko, et al. The Associations of Parity and Maternal Age with Small-for-gestational-age, Preterm, and Neonatal and Infant Mortality: a Meta-analysis. BioMed Central Ltd, 2013. https://doi.org/10.17615/b77y-9q55APA
Kozuki, N., Lee, A., Silveira, M., Sania, A., Vogel, J., Adair, L., Barros, F., Caulfield, L., Christian, P., Fawzi, W., Humphrey, J., Huybregts, L., Mongkolchati, A., Ntozini, R., Osrin, D., Roberfroid, D., Tielsch, J., Vaidya, A., Black, R., Katz, J., & Health Epidemiology Reference Group (Cherg) Small For Gestational Age Preterm Birth Working Group, C. (2013). The associations of parity and maternal age with small-for-gestational-age, preterm, and neonatal and infant mortality: a meta-analysis. BioMed Central Ltd. https://doi.org/10.17615/b77y-9q55Chicago
Kozuki, Naoko, Anne Cc Lee, Mariangela F Silveira, Ayesha Sania, Joshua P Vogel, Linda Adair, Fernando Barros et al. 2013. The Associations of Parity and Maternal Age with Small-For-Gestational-Age, Preterm, and Neonatal and Infant Mortality: a Meta-Analysis. BioMed Central Ltd. https://doi.org/10.17615/b77y-9q55- Creator
-
Kozuki, Naoko
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Lee, Anne CC
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Silveira, Mariangela F
- Other Affiliation: Programa de Pós-graduacao em Epidemiologia, Universidade Federal de Pelotas
-
Sania, Ayesha
- Other Affiliation: Department of Epidemiology, Harvard School of Public Health
-
Vogel, Joshua P
- Other Affiliation: School of Population Health, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia
-
Adair, Linda
- Affiliation: Gillings School of Global Public Health
-
Barros, Fernando
- Other Affiliation: Programa de Pós-graduacao em Epidemiologia, Universidade Federal de Pelotas
-
Caulfield, Laura E
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Christian, Parul
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Fawzi, Wafaie
- Other Affiliation: Departments of Nutrition, Epidemiology, and Global Health and Population, Harvard School of Public Health
-
Humphrey, Jean
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Huybregts, Lieven
- Other Affiliation: Department of Food Safety and Food Quality, Ghent University
-
Mongkolchati, Aroonsri
- Other Affiliation: ASEAN Institute for Health Development, Mahidol University
-
Ntozini, Robert
- Other Affiliation: Zvitambo
-
Osrin, David
- Other Affiliation: Institute for Global Health, UCL Institute of Child Health
-
Roberfroid, Dominique
- Other Affiliation: Woman and Child Health Research Center, Department of Public Health, Institute of Tropical Medicine
-
Tielsch, James
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Vaidya, Anjana
- Other Affiliation: Institute for Global Health, UCL Institute of Child Health
-
Black, Robert E
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
-
Katz, Joanne
- Other Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health
- Child Health Epidemiology Reference Group (CHERG) Small-for-Gestational-Age-Preterm Birth Working Group
- Abstract
- Background Previous studies have reported on adverse neonatal outcomes associated with parity and maternal age. Many of these studies have relied on cross-sectional data, from which drawing causal inference is complex. We explore the associations between parity/maternal age and adverse neonatal outcomes using data from cohort studies conducted in low- and middle-income countries (LMIC). Methods Data from 14 cohort studies were included. Parity (nulliparous, parity 1-2, parity ≥3) and maternal age (<18 years, 18-<35 years, ≥35 years) categories were matched with each other to create exposure categories, with those who are parity 1-2 and age 18-<35 years as the reference. Outcomes included small-for-gestational-age (SGA), preterm, neonatal and infant mortality. Adjusted odds ratios (aOR) were calculated per study and meta-analyzed. Results Nulliparous, age <18 year women, compared with women who were parity 1-2 and age 18-<35 years had the highest odds of SGA (pooled adjusted OR: 1.80), preterm (pooled aOR: 1.52), neonatal mortality (pooled aOR: 2.07), and infant mortality (pooled aOR: 1.49). Increased odds were also noted for SGA and neonatal mortality for nulliparous/age 18-<35 years, preterm, neonatal, and infant mortality for parity ≥3/age 18-<35 years, and preterm and neonatal mortality for parity ≥3/≥35 years. Conclusions Nulliparous women <18 years of age have the highest odds of adverse neonatal outcomes. Family planning has traditionally been the least successful in addressing young age as a risk factor; a renewed focus must be placed on finding effective interventions that delay age at first birth. Higher odds of adverse outcomes are also seen among parity ≥3 / age ≥35 mothers, suggesting that reproductive health interventions need to address the entirety of a woman’s reproductive period. Funding Funding was provided by the Bill & Melinda Gates Foundation (810-2054) by a grant to the US Fund for UNICEF to support the activities of the Child Health Epidemiology Reference Group.
- Date of publication
- September 17, 2013
- DOI
- Identifier
- Resource type
- Article
- Rights statement
- In Copyright
- Rights holder
- Naoko Kozuki et al.; licensee BioMed Central Ltd.
- License
- Journal title
- BMC Public Health
- Journal volume
- 13
- Journal issue
- Suppl 3
- Page start
- S2
- Language
- English
- Is the article or chapter peer-reviewed?
- Yes
- Bibliographic citation
- BMC Public Health. 2013 Sep 17;13(Suppl 3):S2
- Publisher
- BioMed Central Ltd
- Access right
- Open Access
- Date uploaded
- January 22, 2016
Relations
- Parents:
This work has no parents.
Items
Thumbnail | Title | Date Uploaded | Visibility | Actions |
---|---|---|---|---|
12889_2013_article_5775.pdf | 2019-05-07 | Public | Download | |
12889_2013_5775_moesm1_esm.pdf | 2019-05-07 | Public | Download |